DR.  Masoud  KHoshnia

Gastroenterologist

Biography:

Name: Masoud
Family name: Khoushnia
Date of birth: August  23, 1975
Place of birth: Bandar Turkaman, Iran
Nationality: Islamic Republic of Iran

Education:

-Fellowship,Endosonography                         Tehran University of Medical Sciences          2012-2013
-Fellowship ,Advance endoscopy, EUS/ERCP    Charite Medical University of Berlin,
                                                                               Charite Campus Virchow   klinikum,   
                                                                                Berlin,Germany                                      2009-2010
-Subspecialty (Gastroenterol and Hepatol)    Tehran University of Medical Sciences     2006-2009
-Speciality, internal medicine            Tehran University of Medical Sciences     2001-2005
-General Medicine                Mashhad University of Medical Sciences     1993-2000

Other trainings:
-Observership(guest doctor) in EUS/Endoscopy          University Klinikum Eppendorf ,                  
                                                                                        Hamburg University,Hamburg,Germany   2010                     

-Post graduate course in gastroenterology                Free university medical center,Amesterdam     2009

Academic Positions:

Assistant professor of medicine
Digestive Diseases Research Institute, Tehran  University of Medical Sciences, Tehran, Iran , 2014-present
                                                                                                                              

  -Golestan University of Medical Sciences,Faculty of medicine   
            -Training of medical students
             -Training of asistant,internal medicine ,2009-present

-Scientific Staff of Advance Endoscopy Education Program
                                            -EUS Fellowship Program,Shariati hospital,
                                            Tehran University of Medical Sciences,Tehran,Iran                2014-Present    

-Vice- chancellar for Research and technology ,Golestan University of Medical Sciences    2014-2015

-Deputy in Faculty of medicine ,Golestan University of Medical Sciences                               2013-2014    
 
-  Co- PI  of  Golestan Cohort  Study(GCS) : the first large-scale cohort study in the Middle East and North Africa     2012-Present            

Membership in scientific professional organizations:

- Iranian society of gastroenterology and hepatology                        since 2009
- Research Council of Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences                                since 2009
- Research Council of Golestan University of Medical Sciences                2010-2014

Publications:

1. Khoshnia M, Pourshams A, Mohammadkhani A, Tavangar SM, Shahbazkhani B, Malekzadeh R. Celiac Disease in Gonbad-Kavoos. Govaresh 2005; 10(3): 131-33.

2. Khoshnia M, Vahedi H. Case Report Churg-Strauss Vasculitis with Gastrointestinal Manifestations During Tapering of Prednisolone. Govaresh 2007; 12(3): 173-212.

3. Jamali R, Khonsari M, Merat S, Khoshnia M, Jafari E, Bahram Kalhori A, Abolghasemi H, Amini S, Maghsoudlu M, Deyhim MR, Rezvan H, Pourshams A. Persistent alanine aminotransferase elevation among the general Iranian population: prevalence and causes. World J Gastroenterol 2008; 14(18): 2867-71.

4. Khoshnia M, Vahedi H.  "Case Report" Wegner's Granulomatosis with Gastrointestinal Manifestation. Govaresh 2009; 13(4): 253-256.

5. Malekzadeh F, Marshall T, Pourshams A, Gharravi M, Aslani A, Nateghi A, Rastegarpanah M, Khoshnia M, Semnani S, Salahi R, Thomas GN, Larijani B, Cheng KK, Malekzadeh R. A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors. Int J Clin Pract. 2010; 64(9):1220-7.

6. Khoshnia M, Islami F,Aghcheli K, Malekzadeh R, PourshamsA.Celiac Disease and Esophageal Cancer.GOVARESH 2012; 17(2) ;73-78
7. Roshandel G, Nourouzi A, Pourshams A, Semnani S, Merat S, Khoshnia M. Endoscopic screening for esophageal squamous cell carcinoma.Arch Iran Med. 2013 Jun;16(6):351-7.

8.Ghasemi-Kebria F, Roshandel G, Semnani S, Shakeri R, Khoshnia M, Naeimi-Tabiei M, Merat S, Malekzadeh R.Marked increase in the incidence rate of esophageal adenocarcinoma in a high-risk area for esophageal cancer.Books Arch Iran Med. 2013 Jun;16(6):320-3.

9.Shakeri R, Malekzadeh R, Etemadi A, Nasrollahzadeh D, Abedi-Ardekani B, Khoshnia M, Islami F, Pourshams A, Pawlita M, Boffetta P, Dawsey SM, Kamangar F, Abnet CC. Association of tooth loss and oral hygiene with risk of gastric adenocarcinoma. Cancer Prev Res (Phila). 2013 May;6(5):477-82.

10. Normal limit for serum alanine aminotransferase level and distribution of metabolic factors in old population of kalaleh, iran.Kabir A, Pourshams A, Khoshnia M, Malekzadeh F.Hepat Mon. 2013 Oct 20;13(10)

11. Opium use and risk of mortality from digestive diseases: a prospective cohort study.Malekzadeh MM, Khademi H, Pourshams A, Etemadi A, Poustchi H, Bagheri M, Khoshnia M, Sohrabpour AA, Aliasgari A, Jafari E, Islami F, Semnani S, Abnet CC, Pharoah PD, Brennan P, Boffetta P, Dawsey SM, Malekzadeh R, Kamangar F.Am J Gastroenterol. 2013 Nov;108(11):1757-65.

12. Endoscopic screening for esophageal squamous cell carcinoma.Roshandel G, Nourouzi A, Pourshams A, Semnani S, Merat S, Khoshnia M.Arch Iran Med. 2013 Jun;16(6):351-7

13. Marked increase in the incidence rate of esophageal adenocarcinoma in a high-risk area for esophageal cancer.Ghasemi-Kebria F, Roshandel G, Semnani S, Shakeri R, Khoshnia M, Naeimi-Tabiei M, Merat S, Malekzadeh R.Arch Iran Med. 2013 Jun;16(6):320-3

14. Pilot study of cytological testing for oesophageal squamous cell dysplasia in a high-risk area in Northern Iran.Roshandel G, Merat S, Sotoudeh M, Khoshnia M, Poustchi H, Lao-Sirieix P, Malhotra S, O'Donovan M, Etemadi A, Nickmanesh A, Pourshams A, Norouzi A, Debiram I, Semnani S, Abnet CC, Dawsey SM, Fitzgerald RC, Malekzadeh R.Br J Cancer. 2014 Dec 9;111(12):2235-41.

15. Gastroesophageal Reflux Disease and overall and Cause-specific Mortality: A Prospective Study of 50000 Individuals.Islami F, Pourshams A, Nasseri-Moghaddam S, Khademi H, Poutschi H, Khoshnia M, Norouzi A, Amiriani T, Sohrabpour AA, Aliasgari A, Jafari E, Semnani S, Abnet CC, Pharaoh PD, Brennan P, Kamangar F, Dawsey SM, Boffetta P, Malekzadeh R.Middle East J Dig Dis. 2014 Apr;6(2):65-80.

16. Endoscopic screening for precancerous lesions of the esophagus in a high risk area in Northern Iran.Roshandel G, Khoshnia M, Sotoudeh M, Merat S, Etemadi A, Nickmanesh A, Norouzi A, Pourshams A, Poustchi H, Semnani S, Ghasemi-Kebria F, Noorbakhsh R, Abnet C, Dawsey SM, Malekzadeh R.Iran Med. 2014 Apr;17(4):246-52.

17. Determinants of gastroesophageal reflux disease, including hookah smoking and opium use- a cross-sectional analysis of 50,000 individuals.Islami F, Nasseri-Moghaddam S, Pourshams A, Poustchi H, Semnani S, Kamangar F, Etemadi A, Merat S, Khoshnia M, Dawsey SM, Pharoah PD, Brennan P, Abnet CC, Boffetta P, Malekzadeh R.PLoS One. 2014 Feb 21;9(2)

18. Impact of body size and physical activity during adolescence and adult life on overall and cause-specific mortality in a large cohort study from Iran.Etemadi A, Abnet CC, Kamangar F, Islami F, Khademi H, Pourshams A, Poustchi H, Bagheri M, Sohrabpour AA, Aliasgar A, Khoshnia M, Wacholder S, Matthews CC, Pharoah PD, Brennan P, Boffetta P, Malekzadeh R, Dawsey SM.Eur J Epidemiol. 2014 Feb;29(2):95-109

19. PolyPill for Prevention of Cardiovascular Disease in an Urban Iranian Population with Special Focus on Nonalcoholic Steatohepatitis: A Pragmatic Randomized Controlled Trial within a Cohort (PolyIran - Liver) - Study Protocol.Merat S, Poustchi H, Hemming K, Jafari E, Radmard AR, Nateghi A, Shiravi Khuzani A, Khoshnia M, Marshall T, Malekzadeh R.Arch Iran Med. 2015 Aug;18(8):515-23

20. Polypill for the prevention of cardiovascular disease (PolyIran): study design and rationale for a pragmatic cluster randomized controlled trial.Ostovaneh MR, Poustchi H, Hemming K, Marjani H, Pourshams A, Nateghi A, Majed M, Navabakhsh B, Khoshnia M, Jaafari E, Mohammadifard N, Malekzadeh F, Merat S, Sadeghi M, Naemi M, Etemadi A, Thomas GN, Sarrafzadegan N, Cheng KK, Marshall T, Malekzadeh R.Eur J Prev Cardiol. 2015 Dec;22(12):1609-17

21. The association between Metabolic Syndrome and serum levels of adiponectin and high sensitive C reactive protein in Gorgan.Sarbijani HM, Khoshnia M, Marjani A.Endocr Metab Immune Disord Drug Targets. 2015 Jun 8.

22. The association between metabolic syndrome and serum levels of malondialdehyde and interleukin-6 in Gorgan. Journal of Postgraduate Medical Institute
2015 | journal-article EID: 2-s2.0-84953404311

23. Serum level of fibroblast growth factor 21 in type 2 diabetic patients with and without metabolic syndrome Journal of Medical Sciences (Faisalabad)
2015 | journal-articleDOI: 10.3923/jms.2015.80.86EID: 2-s2.0-84938258918

24. Serum fetuin a level, liver enzymes activities and insulin resistance in patients with type 2 diabetes Journal of Medical Sciences (Faisalabad)
2015    | journal-article DOI: 10.3923/jms.2015.229.234 EID: 2-s2.0-84948748840

25. Food preparation methods, drinking water source, and esophageal squamous cell carcinoma in the high-risk area of Golestan, Northeast Iran.Golozar A, Etemadi A, Kamangar F, Fazeltabar Malekshah A, Islami F, Nasrollahzadeh D, Abedi-Ardekani B, Khoshnia M, Pourshams A, Semnani S, Marjani HA, Shakeri R, Sotoudeh M, Brennan P, Taylor P, Boffetta P, Abnet C, Dawsey S, Malekzadeh R.Eur J Cancer Prev. 2016 Mar;25(2):123-9.

26. Serum Progranulin Levels in Type 2 Diabetic Patients with Metabolic Syndrome.Shafaei A, Marjani A, Khoshnia M.Rom J Intern Med. 2016 Dec 1;54(4):211-216.

27. Esophageal Cancer in Golestan Province, Iran: A Review of Genetic Susceptibility and Environmental Risk Factors.Gholipour M, Islami F, Roshandel G, Khoshnia M, Badakhshan A, Moradi A, Malekzadeh R.Middle East J Dig Dis. 2016 Oct;8(4):249-266.

28. Linc-ROR and its spliced variants 2 and 4 are significantly up-regulated in esophageal squamous cell carcinoma.Sahebi R, Malakootian M, Balalaee B, Shahryari A, Khoshnia M, Abbaszadegan MR, Moradi A, Javad Mowla S.Iran J Basic Med Sci. 2016 Oct;19(10):1131-1135.

29.Immune responses to hepatitis B immunization 10-18 years after primary vaccination: a population-based cohort study.Katoonizadeh A, Sharafkhah M, Ostovaneh MR, Norouzi A, Khoshbakht N, Mohamadkhani A, Eslami L, Gharravi A, Shayanrad A, Khoshnia M, Esmaili S, George J, Poustchi H, Malekzadeh R.J Viral Hepat. 2016 Oct;23(10):805-11.

30. The Nail as a Biomonitor of Trace Element Status in Golestan Cohort Study.Hashemian M, Poustchi H, Pourshams A, Khoshnia M, Brockman JD, Hekmatdoost A, Abnet CC, Malekzadeh R.Middle East J Dig Dis. 2016 Jan;8(1):19-23.

31. Chronic hepatitis B infection is not associated with increased risk of vascular mortality while having an association with metabolic syndrome.Katoonizadeh A, Ghoroghi S, Sharafkhah M, Khoshnia M, Mirzaei S, Shayanrad A, Poustchi H, Malekzadeh R.J Med Virol. 2016 Jul;88(7):1230-7.

32. The association between Metabolic Syndrome and serum levels of lipid peroxidation and interleukin-6 in Gorgan.Sarbijani HM, Khoshnia M, Marjani A.Diabetes Metab Syndr. 2016 Jan-Mar;10(1 Suppl 1):S86-9

33. Hazards of cigarettes, smokeless tobacco and waterpipe in a Middle Eastern Population: a Cohort Study of 50 000 individuals from Iran.Etemadi A, Khademi H, Kamangar F, Freedman ND, Abnet CC, Brennan P, Malekzadeh R; Golestan Cohort Study Team.Tob Control. 2017 Nov;26(6):674-682.

34. Toenail mineral concentration and risk of esophageal squamous cell carcinoma, results from the Golestan Cohort Study.Hashemian M, Murphy G, Etemadi A, Poustchi H, Brockman JD, Kamangar F, Pourshams A, Khoshnia M, Gharavi A, Dawsey SM, Brennan PJ, Boffetta P, Hekmatdoost A, Malekzadeh R, Abnet CC.Cancer Med. 2017 Dec;6(12):3052-3059

35. Multimorbidity as an important issue among women: results of a gender difference investigation in a large population-based cross-sectional study in West Asia.Alimohammadian M, Majidi A, Yaseri M, Ahmadi B, Islami F, Derakhshan M, Delavari A, Amani M, Feyz-Sani A, Poustchi H, Pourshams A, Sadjadi AM, Khoshnia M, Qaravi S, Abnet CC, Dawsey S, Brennan P, Kamangar F, Boffetta P, Sadjadi A, Malekzadeh R.BMJ Open. 2017 May 9;7(5)

36. Prevalence and determinants of chronic kidney disease in northeast of Iran: Results of the Golestan cohort study.Sepanlou SG, Barahimi H, Najafi I, Kamangar F, Poustchi H, Shakeri R, Hakemi MS, Pourshams A, Khoshnia M, Gharravi A, Broumand B, Nobakht-Haghighi A, Kalantar-Zadeh K, Malekzadeh R.PLoS One. 2017 May 3;12(5)

37. Oral health and mortality in the Golestan Cohort Study.Vogtmann E, Etemadi A, Kamangar F, Islami F, Roshandel G, Poustchi H, Pourshams A, Khoshnia M, Gharravi A, Brennan PJ, Boffetta P, Dawsey SM, Malekzadeh R, Abnet CC.Int J Epidemiol. 2017 Dec 1;46(6):2028-2035.

38. Dairy Food Intake and All-Cause, Cardiovascular Disease, and Cancer Mortality: The Golestan Cohort Study.Farvid MS, Malekshah AF, Pourshams A, Poustchi H, Sepanlou SG, Sharafkhah M, Khoshnia M, Farvid M, Abnet CC, Kamangar F, Dawsey SM, Brennan P, Pharoah PD, Boffetta P, Willett WC, Malekzadeh R.Am J Epidemiol. 2017 Apr 15;185(8):697-711

39. White rice intake and incidence of type-2 diabetes: analysis of two prospective cohort studies from Iran.Golozar A, Khalili D, Etemadi A, Poustchi H, Fazeltabar A, Hosseini F, Kamangar F, Khoshnia M, Islami F, Hadaegh F, Brennan P, Boffetta P, Abnet CC, Dawsey SM, Azizi F, Malekzadeh R, Danaei G.BMC Public Health. 2017 Jan 31;17(1):133

40. Dietary Protein Sources and All-Cause and Cause-Specific Mortality: The Golestan Cohort Study in Iran.Farvid MS, Malekshah AF, Pourshams A, Poustchi H, Sepanlou SG, Sharafkhah M, Khoshnia M, Farvid M, Abnet CC, Kamangar F, Dawsey SM, Brennan P, Pharoah PD, Boffetta P, Willett WC, Malekzadeh R.Am J Prev Med. 2017 Feb;52(2):237-248

41.Mortality from respiratory diseases associated with opium use: a population-based cohort study.Rahmati A, Shakeri R, Khademi H, Poutschi H, Pourshams A, Etemadi A, Khoshnia M, Sohrabpour AA, Aliasgari A, Jafari E, Islami F, Semnani S, Gharravi A, Abnet CC, Pharoah PDP, Brennan P, Boffetta P, Dawsey SM, Malekzadeh R, Kamangar F.Thorax. 2017 Nov;72(11):1028-1034.

42. Is There Any Evidence for a Viral Cause in Achalasia?
Moradi A, Fazlollahi N, Eshraghi A, Gholipour M, Khoshnia M, Javid N, Montazeri SA, Mikaeli J.
Middle East J Dig Dis. 2018 Jul;10(3):169-173.

43. Micro-RNAs -106a and -362-3p in Peripheral Blood of Inflammatory Bowel Disease Patients.
Omidbakhsh A, Saeedi M, Khoshnia M, Marjani A, Hakimi S.
Open Biochem J. 2018 Jun 29;12:78-86.

44. Opium Use and Risk of Pancreatic Cancer: A Prospective Cohort Study.Moossavi S, Mohamadnejad M, Pourshams A, Poustchi H, Islami F, Sharafkhah M, Mirminachi B, Nasseri-Moghaddam S, Semnani S, Shakeri R, Etemadi A, Merat S, Khoshnia M, Dawsey SM, Pharoah PD, Brennan P, Abnet CC, Boffetta P, Kamangar F, Malekzadeh R.Cancer Epidemiol Biomarkers Prev. 2018 Mar;27(3):268-273

45. Causes of premature death and their associated risk factors in the Golestan Cohort Study, Iran.
Nalini M, Oranuba E, Poustchi H, Sepanlou SG, Pourshams A, Khoshnia M, Gharavi A, Dawsey SM, Abnet CC, Boffetta P, Brennan P, Sotoudeh M, Nikmanesh A, Merat S, Etemadi A, Shakeri R, Sohrabpour AA, Nasseri-Moghaddam S, Kamangar F, Malekzadeh R.
BMJ Open. 2018 Jul 18;8(7)

46. Nut consumption and the risk of oesophageal squamous cell carcinoma in the Golestan Cohort Study.Hashemian M, Murphy G, Etemadi A, Poustchi H, Sharafkhah M, Kamangar F, Pourshams A, Malekshah AF, Khoshnia M, Gharavi A, Hekmatdoost A, Brennan PJ, Boffetta P, Dawsey SM, Abnet CC, Malekzadeh R.
Br J Cancer. 2018 Jul;119(2):176-181.

Translation:
1.Translation :Harrison,s text book of internal medicine,chapter:Gastroenterology,2008
2.Translation :Harrison,s text book of internal medicine,chapter:Hepatology ,2008

THESIS:supervisor/advisor

1.Evaluation of 10 fungal metabolites in urine excretion of esophageal squamous cell carcinoma , patients and control group with GC/MS methods, Residency graduation of internal medicine,Faculty of medicine ,Golestan university of medical sciences

2.Determination of  micro-RNAs -106a and -362-3p expression in the patient with ulcerative colitis and crohn diseases,Faculty of medicine,Golestan university of medical sciences

3.Determination of  H.Pylori  antibiotic resistancy in the gastric biopsy species with PCR-RFLP. Faculty of medicine,Golestan university of medical sciences

4.Comparison of  two regimen furazolidon base quadriple therapy for H.Pylori eradication in peptic ulcer disease, Faculty of medicine,Golestan university of medical sciences

5.Evaluation of strontium and antimony in the Squamous cell carcinoma and healthy cases, Faculty of medicine,Golestan university of medical sciences

6.Comparison of adiponectin serum level ,lipid peroxidation , high sensitive CRP level and IL-1 the metabolic syndrome and healthy cases, Faculty of medicine,Golestan university of medical sciences

7.Evaluation of aminoacid profile in the Squamous cell carcinoma and healthy cases,  Faculty of medicine,Golestan university of medical sciences

8.Evaluation of barotrauma after colonoscopy, Faculty of medicine,Golestan university of medical sciences
9.Comparison of fibroscan,nuclear  scan and liver biopsy in chronic hepatitis, Faculty of medicine, Golestan university of medical sciences

10.Comparison of Alanine amino transferase (ALT) in patient with normal coronary angiography and  abnormal coronary artery angiography , Faculty of medicine,Golestan university of medical sciences

11.Evaluation of five year endoscopic findings in the endoscopy ward of 5 azar hospital in  gorgan, Faculty of medicine,Golestan university of medical sciences

12.Evaluation of fibroblastic growth factor 21( FGF-21) in the patient with and without metabolic syndrome, Faculty of medicine,Golestan university of medical sciences

Contact:

Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Tel: (+98 21)82415555

Cell phone: +98 911 178 6541
Fax: (+98 21)82415400

Email:  khoshniamd@gmail.com

Address: Shariati Hospital, North Kargar Ave ,Tehran,Iran
                                           
Golestan Research Center of Gastroenterology and Hepatology,
 Sayad shirazi hospital, Gorgan, Iran

 

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